The European Genome-phenome Archive (EGA) is a service for permanent archiving and sharing of all types of personally identifiable genetic and phenotypic data resulting from biomedical research projects.
  • Latest studies

    Multi-omics highlights ABO plasma protein as a causal risk factor for COVID-19. – 2021-02-19

    Human pQTLs using UK INTERVAL (Cambridge CEU) plasma samples. pQTL mapping of 3,283 protein analytes assayed using SomaLogic SOMAscan, across 10.6M imputed genetic variants, in 3,301 samp Read more

     Study 1 / 5

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  • Latest studies

    Genome-wide detection of cytosine methylation by single molecule real-time sequencing. – 2021-02-01

    5-methylcytosine (5mC) is an important type of epigenetic modification. In this study, we enhanced 5mC detection using SMRT sequencing by holistically analyzing kinetic signals of a DNA p Read more

     Study 2 / 5

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  • Latest studies

    Population collapse in Congo rainforest from 400 CE urges reassessment of the Bantu Expansion. – 2021-02-12

    Bantu languages are spoken by ~310 million Africans, yet the genetic history of Bantu-speaking populations remains largely unexplored. We generated genomic data for 1,318 individuals from Read more

     Study 3 / 5

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    Nanopore sequencing from liquid biopsy: analysis of copy number variations from cell-free DNA of lung cancer patients. – 2021-02-12

    In the "precision oncology" era the characterization of tumor genetic features is a pivotal step in cancer patients' management. Liquid biopsy approaches, such as analysis of cell-free DN Read more

     Study 4 / 5

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  • Latest studies

    Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma. – 2021-02-05

    Immune checkpoint inhibitors targeting the PD-1 pathway have transformed the management of many advanced malignancies, including clear cell renal cell carcinoma (ccRCC), but the drivers a Read more

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  • What is in the EGA?